| Anchorage School District | Anchorage | PK–12 | 42,573 |
| Matanuska-Susitna Borough School District | Palmer | PK–12 | 19,495 |
| Fairbanks North Star Borough School District | Fairbanks | PK–12 | 11,857 |
| Kenai Peninsula Borough School District | Soldotna | PK–12 | 8,510 |
| Galena City School District | Galena | PK–12 | 8,168 |
| Juneau Borough School District | Juneau | PK–12 | 4,085 |
| Yukon-Koyukuk School District | Fairbanks | PK–12 | 4,024 |
| Lower Kuskokwim School District | Bethel | PK–12 | 3,823 |
| Nenana City School District | Nenana | PK–12 | 2,279 |
| Kodiak Island Borough School District | Kodiak | PK–12 | 2,122 |
| Ketchikan Gateway Borough School District | Ketchikan | PK–12 | 2,043 |
| Lower Yukon School District | Mountain Village | PK–12 | 2,027 |
| Northwest Arctic Borough School District | Kotzebue | PK–12 | 1,945 |
| North Slope Borough School District | Utqiagvik | PK–12 | 1,853 |
| Bering Strait School District | Unalakleet | PK–12 | 1,745 |
| Sitka School District | Sitka | PK–12 | 1,080 |
| Denali Borough School District | Healy | PK–12 | 1,073 |
| Delta/greely School District | Delta Junction | PK–12 | 971 |
| Nome Public Schools | Nome | PK–12 | 672 |
| Chugach School District | Anchorage | PK–12 | 617 |
| Craig City School District | Craig | PK–12 | 615 |
| Southwest Region School District | Dillingham | PK–12 | 615 |
| Valdez City School District | Valdez | PK–12 | 605 |
| Yupiit School District | Akiachak | K–12 | 522 |
| Petersburg Borough School District | Petersburg | PK–12 | 464 |
| Mount Edgecumbe | Sitka | 9–12 | 422 |
| Dillingham City School District | Dillingham | PK–12 | 403 |
| Copper River School District | Glennallen | PK–12 | 393 |
| Alaska Gateway School District | Tok | PK–12 | 381 |
| Cordova City School District | Cordova | PK–12 | 361 |
| Unalaska City School District | Unalaska | PK–12 | 337 |
| Lake and Peninsula Borough School District | King Salmon | PK–12 | 320 |
| Kashunamiut School District | Chevak | PK–12 | 320 |
| Kuspuk School District | Aniak | PK–12 | 309 |
| Annette Island School District | Metlakatla | PK–12 | 301 |
| Wrangell Public School District | Wrangell | PK–12 | 264 |
| Iditarod Area School District | Mcgrath | PK–12 | 263 |
| Haines Borough School District | Haines | PK–12 | 255 |
| Aleutians East Borough School District | Sand Point | PK–12 | 178 |
| Saint Mary's School District | Saint Mary's | PK–12 | 178 |
| Yukon Flats School District | Ft. Yukon | PK–12 | 175 |
| Southeast Island School District | Thorne Bay | PK–12 | 164 |
| Chatham School District | Angoon | PK–12 | 161 |
| Skagway School District | Skagway | PK–12 | 138 |
| Klawock City School District | Klawock | PK–12 | 127 |
| Kake City School District | Kake | PK–12 | 117 |
| Hydaburg City School District | Hydaburg | PK–12 | 117 |
| Hoonah City School District | Hoonah | PK–12 | 110 |
| Bristol Bay Borough School District | Naknek | PK–12 | 106 |
| Yakutat School District | Yakutat | PK–12 | 95 |
| Pribilof School District | St. Paul Island | PK–12 | 65 |
| Aleutian Region School District | Anchorage | K–12 | 21 |
| Pelican City School District | Pelican | K–12 | 12 |
| Tanana City School District | Closed | — | — |